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Centre for Integrative Physiology
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Imaging of synaptic vesicle turnover using FM4-64 Model mammalian  morphogenesis - real renal collecting duct growing in vitro Model mammalian  morphogenesis - computer model of collecting duct 'growing' in silico Stripes in the cornea of a mouse F-actin cytoskeleton in bovine chondrocyte cells TO-PRO3 labelling of DNA in dividing cells Actin and tubulin cytoskeletal labelling of cells Rat retina flat mount - astrocyte (red) and artery (green) interaction with vein Whole mount E10.5 embryo Detail from adult testes - PI nuclear counterstain

    Advanced Medical Science Course



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Advance Medical Science website

Advanced Medical Science Course in
The Centre for Integrative Physiology
(University of Edinburgh)


For Medical Students in their AMS Year at the University of Melbourne

Opportunities at the University of Edinburgh


WELCOME to the Centre for Integrative Physiology (CIP) at The University of Edinburgh. We are pleased to invite you to do a research project in Edinburgh for your AMS year.

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CIP

Edinburgh Centre for Integrative Physiology (CIP) contains three major research groupings, each carrying out leading-edge research in molecular, cellular and systems physiology.

Research in the CIP extends from studies of membrane ion channel function and dysfunction in tissues including brain, mechanisms of hormone and neurotransmitter release, regulation of cell volume in articular chondrocytes in osteoarthritis, the cellular and systems-level actions of stress steroids, regulation of growth, appetite and obesity by neuroendocrinological control systems, neuroendocrine adaptations in pregnancy, brain control of reproductive behaviours including sexual behaviour and aggression, mechanisms of brain plasticity in motor control and motor learning, and molecular and cellular mechanisms of development of various tissues including in the brain, ovarian follicle, kidney and mammary gland.

For further details of research areas available for AMS student projects this year please see below the list of CIP staff offering projects.

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The AMS Course available in the CIP

We provide laboratory-based projects that will train you in basic laboratory techniques (at the molecular, cell, organ or whole-animal level), experimental design, data collection and analysis, and scientific presentation, through working on a research project of your choice selected from those on offer from the members of the CIP.

Course Details

Assessment – 100% research (90% dissertation & 10% oral presentation)
Maximum numbers per year – 5

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Application Procedure

In the first instance you should submit the following to Shirley Linton at the address below:

  • your CV
  • name of one referee
  • a covering letter including a written statement on why you would like to do your research project in the CIP at The University of Edinburgh

You may contact staff from the list below to discuss potential projects that you might be interested in at this stage. The CIP will review your CV and statement and make offers to individual students as appropriate. The selected student(s) will then choose the project they desire, in discussion with the AMS co-ordinator and members of CIP staff.

Individual projects will be available in various laboratories in the CIP, and the student(s) offered a place will be expected to select a project by discussion with staff members. For a list of staff members offering projects this year for University of Melbourne AMS student please see below.

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Sample Research Topics

  • Role of protein phosphorylation in synapic vesicle recycling (Supervisor: Dr M Cousin)
  • Brain and pituitary mechanisms underlying stress-induced spontaneous miscarriage (Supervisor: Dr AJ Douglas)
  • Regulation of forebrain development by the transcription factor Pax6 (Supervisor: Prof D Price)
  • Lifecycle of a potassium channel (Supervisor: Professor MJ Shipston)
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List of CIP staff offering projects
(click on link for further information about each staff member):

Dr Douglas Armstrong Characterising the role of genes involved in human cognition and mental health in the brain and behaviour of simple model organisms
Dr Mike Cousin Mechanism of synaptic vesicle recycling and neurotransmitter release in epilepsy
Dr Alison J Douglas Neuroendocrine mechanisms of stress-induced miscarriage
Dr Peter Flatman Regulating cell content in health and disease
Dr Tom Gillingwater Neurodegeneration and neuroprotection in synapses and axons
Dr Andrew Hall What role do articular chondrocytes play in the development of osteoarthritis?
Professor Andrew Jarman Genetic regulation of neural development in Drosophila
Dr Peter Kind  
Professor Gareth Leng Hypothalamic regulation of appetite
Dr Mike Ludwig Mechanisms of dendritic exocytosis
Dr Sutherland Maciver The role of gelsolin and scinderin in actin cytoskeleton remodelling during regulated secretion
Dr John Mason Embryonic development of the mouse forebrain
Professor David Price How the brain is built; the molecular genetics of morphological development
Professor John Russell The role of attenuated neuroendocrine stress responses in pregnancy in protecting the offspring from adverse programming
Professor Jonathan Seckl Tissue metabolism of glucocorticoids: causing and treating the metabolic syndrome
Professor Mike Shipston  
Dr Norah Spears The development of the mammalian ovary
Dr Rolly Wiegand Studies of the regulation of vesicle trafficking from the Golgi apparatus to the regulated secretory pathway using imaging approaches
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Further information

Students will also be expected to attend regular seminars and presentations in the CIP and associated laboratories, to gain an overall view of current research issues in biomedical science

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Contacts

Co-ordinator:
Dr Alison J Douglas
Senior Lecturer
Centre for Integrative Physiology
Hugh Robson Building
George Square
Edinburgh
EH8 9XD
United Kingdom

Email: alison.j.douglas@ed.ac.uk
Tel: +44(0)131 650 3274
Fax: +44(0)131 650 2872

Alternative contact:
Mrs Shirley Linton
Biomedical Teaching Organisation
School of Biomedical Sciences
Medical School
Teviot Place
Edinburgh
EH8 9AG
United Kingdom

Email: shirley.linton@ed.ac.uk
Tel / Fax: +44 (0)131 651 3029

 

 

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Designed and published by Marianne Eastwood (m.eastwood@ed.ac.uk)
© The University of Edinburgh
January 2008