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Genes and Development (G&D) is an Interdisciplinary Research Grouping (IDG) primarily located within the Centre fof Integrative Physiology which is a part of the School of Biomedical Sciences within the College of Medicine and Veterinary Medicine. G&D carries out fundamental research into various aspects of molecular, cellular and developmental biology.

Our aim is to contribute towards gathering and disseminating the essential knowledge required to understand and combat disease in the next millennium.

RESEARCH

Understanding how a complex organism is formed from a single cell is integral to modern biomedical research. It requires a detailed knowledge of gene expression, cell behaviour and cellular interactions, processes which are fundamental to the mechanisms involved in constructing an elaborate, multi-cellular organism. In recent years, the use of molecular techniques for effecting genetic manipulation and the production of transgenic organisms, has had an enormous impact on our understanding of the developmental process and its importance in health and disease. As we expand our knowledge of the mechanisms which regulate the behaviour of developing cells, these advances provide further insight into the causes and potential therapies for congenital abnormalities, cancers and degenerative diseases.

Fuller information is available on the individual members' research pages.

MEMBERS

The full members of the Genes & Development Inter-disciplinary Group within the Centre for Integrative Physiology are shown below. Click on the linked last names for further information where available:-

ASSOCIATE MEMBERS

In addition, there are members in several other areas within the College of Medicine and Veterinary Medicine, including:-

John Ansell (Oncology)
Peter Brophy (Veterinary Biomedical Sciences)
Lesley Forrester (Oncology)
Richard Meehan (MRC SS, MRC HGU)
Steve Morley (Clinical Biochemistry)
Sari Pennings (Senior Lecturer, QMRI CVS)
Philippa Saunders (MRC Unit of Reproductive Biology)
Irina Stancheva (CR UK Senior Research Fellow, ICMB)
Ian Whittle (Clinical Neurosciences)
Val Wilson (Centre for Genome Research)

The Laboratory Manager for the IDG is Tom Pratt.

DATABASES

Genes & Development publish and contribute to the following databases:

• Edinburgh Human Developmental Anatomy (EHDA) - human embryo taxonomy
• The Kidney Development Database
• Glandular Organ Development Database - databases for lung, mammary, pancreas, prostate and salivary glands
• The Mouse Atlas Project - main home page at the site of our collaborators at the MRC Human Genetics Unit where the mouse anatomy is kept

CONTACT DETAILS

For general information, contact the Convenor of the Genes and Development Group at the address below. If your enquiry relates to a specific research area you should deal directly with the group in question using the contact information provided on the individual members' research pages.